How do humanities disciplines register feelings and meanings associated with vulnerability? One common response to vulnerability, whether for individuals or institutions, inclines toward protectiveness and self-defense, and understandably so. But vulnerability also opens us to transformation. What might the prospects of dynamic change mean in an era of widespread “crisis” in the humanities, when humanities disciplines are increasingly portrayed as indefensible? Might the greatest chance for the survival of the humanities depend, ironically, on how their proponents embrace that very trait?